Where does HPV live in the body?
HPV lives in thin, flat cells called epithelial cells. These are found on the skin’s surface. They’re also found on the surface of the vagina, anus, vulva, cervix and head of the penis.
How does HPV enter body?
You can get HPV by having vaginal, anal, or oral sex with someone who has the virus. It is most commonly spread during vaginal or anal sex. HPV can be passed even when an infected person has no signs or symptoms.
Where can HPV spread to?
There are more than 200 types of human papillomavirus (HPV). About 40 kinds can infect your genital area — your vulva, vagina, cervix, rectum, anus, penis, and scrotum — as well as your mouth and throat. These kinds of HPV are spread during sexual contact.
What is the portal of entry for HPV?
The entry of HPV in vitro is initiated by binding to a cell surface receptor in contrast to the in vivo situation where the basement membrane has recently been identified as the primary site of virus binding.
What is the incubation period for HPV?
The estimated incubation period from HPV infection to genital wart development is 2 weeks to 8 months, with the majority of genital warts appearing 2–3 months after an HPV infection (Oriel, 1971).
What is the life cycle of HPV?
HPV DNA replication during its life cycle occurs in three separate phases (reviewed in [1, 2]). After viral entry into the cell nucleus and the activation of viral gene expression, the viral genome copy number increases to several hundred copies per cell during the initial phase of genome amplification.
Is HPV infection for life?
Depending on the type of HPV that you have, the virus can linger in your body for years. In most cases, your body can produce antibodies against the virus and clear the virus within one to two years. Most strains of HPV go away permanently without treatment.
How do you diagnose HPV?
Your doctor collects a sample of cells from your cervix or vagina to send for laboratory analysis. Pap tests can reveal abnormalities that can lead to cancer. DNA test. This test, conducted on cells from your cervix, can recognize the DNA of the high-risk varieties of HPV that have been linked to genital cancers.