What are replication studies?
Replication is a term referring to the repetition of a research study, generally with different situations and different subjects, to determine if the basic findings of the original study can be applied to other participants and circumstances.
What is an example of replication in science?
Replication is the act of reproducing or copying something, or is a copy of something. When an experiment is repeated and the results from the original are reproduced, this is an example of a replication of the original study. A copy of a Monet painting is an example of a replication.
What is extension paper?
A paper that often accepted in the conference; and there is an opportunity to extend to be published in a journal but after developing almost over %50 from the original one. Best, Cite.
How do you extend a conference paper to a journal?
Add more examples and explanations. Add more data in the form of tables and figures. Reflect on all the hard decisions you made when forcing the conference paper into a small box, and put some of that material back in. The editor or reviewers will do a side‐by‐side comparison of the conference and journal papers.
What is the template for replication?
DNA replication is semiconservative, meaning that each strand in the DNA double helix acts as a template for the synthesis of a new, complementary strand. This process takes us from one starting molecule to two “daughter” molecules, with each newly formed double helix containing one new and one old strand.
What are called Okazaki fragments?
Okazaki fragments are short sequences of DNA nucleotides (approximately 150 to 200 base pairs long in eukaryotes) which are synthesized discontinuously and later linked together by the enzyme DNA ligase to create the lagging strand during DNA replication.
Is the lagging strand synthesized 5 to 3?
Figure 27.27. Okazaki Fragments. At a replication fork, both strands are synthesized in a 5′ → 3′ direction. The leading strand is synthesized continuously, whereas the lagging strand is synthesized in short pieces termed Okazaki fragments.
Where do you find Okazaki fragments?
Relatively short fragment of DNA synthesized on the lagging strand during DNA replication. At the start of DNA replication, DNA unwinds and the two strands splits in two, forming two “prongs” which resemble a fork (thus, called replication fork).
How many Okazaki fragments are there?
Despite the much larger DNA content of eukaryotic compared with prokaryotic cells, Okazaki fragments are ∼1200 nt long in bacteria but only about 200 nt long in eukaryotes (Ogawa and Okazaki 1980). This means that to prepare for every human cell division, >10 million fragments must be made and joined.
How are Okazaki fragments welded together?
How are they welded together? Okazaki fragments are short segments of DNA synthesized away from the replication fork on a template strand during DNA replication. Many such segments are joined together by the enzyme DNA ligase to make up the lagging strand of newly synthesized DNA.
What are the two main components of a chromosome?
Answer : DNA and proteins.
What are the two chemical components of chromosome?
Chapter 16 review
| Question | Answer |
|---|---|
| What are the two chemical components of chromosomes? | Proteins and DNA |
| Why did researchers originally think that protein was the genetic material? | Proteins have great heterogeneity and specificity of function, which were essential for the genetic material. |
What’s meant by the 5 and 3 ends of DNA?
Each end of DNA molecule has a number. One end is referred to as 5′ (five prime) and the other end is referred to as 3′ (three prime). The 5′ and 3′ designations refer to the number of carbon atom in a deoxyribose sugar molecule to which a phosphate group bonds.
Do you read DNA from 5 to 3?
5′ – 3′ direction refers to the orientation of nucleotides of a single strand of DNA or RNA. DNA is always read in the 5′ to 3′ direction, and hence you would start reading from the free phosphate and finish at the free hydroxyl group.
What is 3 end DNA?
3. Each DNA strand has two ends. The 5′ end of the DNA is the one with the terminal phosphate group on the 5′ carbon of the deoxyribose; the 3′ end is the one with a terminal hydroxyl (OH) group on the deoxyribose of the 3′ carbon of the deoxyribose.