Can you have Klinefelter and Down syndrome?

Can you have Klinefelter and Down syndrome?

Double aneuploidies – especially in combination with structural aberrations – are extremely rare among liveborns. The most frequent co-occurrence is of Down (DS) and Klinefelter syndromes (KS) (coincidence 0.098%) [1], because they are common and relatively well tolerated chromosome abnormalities in humans [2].

Is Klinefelter syndrome genetic?

Klinefelter syndrome is not directly inherited – the additional X chromosome occurs as a result of either the mother’s egg or the father’s sperm having the extra X chromosome (an equal chance of this happening in either), so after conception the chromosome pattern is XXY rather than XY.

How is Down syndrome different from Klinefelter and Turner’s syndrome?

Turner syndrome is caused by an absence in one or part of the sex(X) chromosome. Down syndrome is the most common genetic cause of learning disabilities in children. Turner syndrome is the dysgenesis in the female gonads, while Klinefelter syndrome is the male hypogonadism.

What is similar to Klinefelter syndrome?

These conditions include 48,XXXY syndrome, 48,XXYY syndrome, and 49,XXXXY syndrome. Like Klinefelter syndrome, these conditions affect male sexual development and can be associated with learning disabilities and problems with speech and language development.

What is Mosaic Turner Syndrome?

Mosaic Turner syndrome (TS) is a condition in which cells inside the same person have different chromosome packages. Mosaic TS can affect any cell in the body. Some cells have X chromosomes and some don’t. Every 3 out of every 10 girls with TS will have some form of Mosaic TS.

Is Turner syndrome dominant or recessive?

Sex. Turner syndrome only occurs in females. Noonan syndrome, sometimes inappropriately called male Turner syndrome, can occur in males or females. It is an autosomal dominant genetic disorder and is not a chromosomal disorder.

Is there a genetic test for Turner syndrome?

A genetic test called a karyotype analysis can confirm a Turner syndrome diagnosis. This test requires a blood draw. It can determine whether one of the X chromosomes is fully or partially missing.