Does grapefruit interfere with beta blockers?

Does grapefruit interfere with beta blockers?

If you eat grapefruit or drink grapefruit juice at all, be aware that the fruit interacts with several classes of drugs, including statins (taken to lower cholesterol), beta blockers (used to treat heart disease and regulate blood pressure), immune suppressing drugs, psychotropic drugs, and even certain anesthetics.

What can you not take with sotalol?

There are some medicines that may interfere with the way sotalol works. Tell your doctor if you’re taking: medicines that can cause abnormal heart rhythms – these include some antibiotics, like clarithromycin and erythromycin, and some antidepressants, like citalopram and amitripyline.

Can I drink grapefruit juice with sotalol?

Call your doctor at once if you have any of these symptoms. In some patients grapefruits and grapefruit juice may decrease the efficacy of losartan. Grapefruits and grapefruit juice should be avoided if an interaction is suspected. Orange juice is not expected to interact.

Is sotalol a high risk medication?

Sotalol can cause life threatening ventricular tachycardia associated with QT interval prolongation. If the QT interval prolongs to 500 msec or greater, reduce the dose, lengthen the dosing interval, or discontinue the drug.

Is sotalol hard on the kidneys?

Its pharmacokinetic properties may lead to increased serum levels of the drug in patients with reduced kidney function. We report on a case in which kidney failure in a patient using sotalol for paroxysmal atrial fibrillation gave rise to torsade de pointes ventricular tachycardia and, eventually, sudden death.

Can sotalol make you gain weight?

Sotalol may cause heart failure in some patients. Check with your doctor right away if you are having chest pain or discomfort, dilated neck veins, extreme fatigue, irregular breathing, an irregular heartbeat, swelling of the face, fingers, feet, or lower legs, or weight gain.

Does sotalol cause memory loss?

Common side effects of sotalol include bradycardia, hypotension, fatigue, dizziness, depression, memory loss, impotence, cold limbs and, less commonly, severe hypotension, heart failure and bronchospasm. Sudden withdrawal can trigger rebound hypertension.

What can replace sotalol?

Dronedarone: an alternate choice to sotalol and amiodarone in the treatment of atrial fibrillation/flutter in patients who have coronary heart disease.

What are the long term side effects of sotalol?

• Abdominal or stomach pain or swelling.
• body aches or pain.
• burning, crawling, itching, numbness, prickling, “pins and needles”, or tingling feelings.
• cough or hoarseness.
• decreased alertness.
• difficulty with speaking.
• dilated neck veins.
• double vision.

Is sotalol safe for long term use?

The results of our study suggest that sotalol is effective for selected patients with drug refractory ventricular arrhythmias. Although the incidence of side effects are high, patients appear to tolerate long-term sotalol therapy well.

What are the side effects of sotalol 80 mg?

What Are Side Effects Associated with Using Sotalol?

• serious difficulty breathing.
• dizziness.
• fatigue.
• slow heart rate.
• chest pain.
• strong, irregular heartbeat.
• weakness.
• lightheadedness.

Which is better sotalol or metoprolol?

Conclusion: Sotalol is a safe and effective agent for control of heart rate in digitalized patients with atrial fibrillation. Sotalol is superior to metoprolol at submaximal exercise, resulting in better rate control during daily activities.

How much does sotalol affect blood pressure?

The side effects that you have to be aware of is, since it’s a beta blocker and blocks the adrenaline to the heart, it can slow your heart rate, and it’s a blood pressure medicine. It actually can drop your blood pressure a little bit.

Can you take metoprolol and sotalol together?

Interactions between your drugs No interactions were found between metoprolol and sotalol.

How much metoprolol can I take for AFIB?

For heart rate control in a non-acute setting and chronic maintenance therapy† (metoprolol tartrate). 25 to 100 mg PO twice daily. Clinical practice guidelines recommend the use of beta blockers to control the ventricular rate for patients with paroxysmal, persistent, or permanent atrial fibrillation.

What is the safest blood thinner for AFib?

Non–vitamin K oral anticoagulants (NOACs) are now recommended as the preferred alternative to warfarin for reducing the risk of stroke associated with atrial fibrillation (AFib), according to a focused update to the 2014 American Heart Association/American College of Cardiology/Heart Rhythm Society Guideline for the …

What is the best beta blocker for AFib?

Bisoprolol* or metoprolol succinate are first-choice beta-blockers for patients with atrial fibrillation as they are prescribed once-daily and do not require dose adjustment in patients with renal impairment. Bisoprolol is preferred as it is more cardioselective than metoprolol and may cause more bradycardia.

Can you eat grapefruit while taking metoprolol tartrate?

Grapefruits and grapefruit juice should be avoided if an interaction is suspected. Orange juice is not expected to interact.

What does metoprolol do to your body?

Metoprolol is a type of medicine called a beta blocker. Like other beta blockers, metoprolol works by changing the way your body responds to some nerve impulses, especially in the heart. It slows down your heart rate and makes it easier for your heart to pump blood around your body.

Does everyone gain weight on metoprolol?

Yes. Weight gain can occur as a side effect of some beta blockers, especially the older ones, such as atenolol (Tenormin) and metoprolol (Lopressor, Toprol-XL). The average weight gain is about 2.6 pounds (about 1.2 kilograms).

Does metoprolol suppress appetite?

Suppression of this receptor’s activity can stimulate appetite. Prescribed for hypertension and heart attack prevention, older beta blockers, such as metoprolol (Lopressor) and atenolol (Tenormin), can cause sluggishness, reduced activity, low motivation to exercise and weight creep.

What happens if I suddenly stop taking metoprolol?

Don’t stop taking metoprolol suddenly. If you do, you may experience worse chest pain, a jump in blood pressure, or even have a heart attack. Stopping metoprolol is not recommended. If you need to stop taking the drug, first talk to your doctor.

Does metoprolol make you urinate a lot?

This effect may increase the amount of urine you make when you first start the medication. It also helps relax the blood vessels so that blood can flow more easily.

Does metoprolol slow metabolism?

Beta-blockers—especially older ones like atenolol and metoprolol—can lead to weight gain, possibly due to slowing metabolism. During the first few months of treatment, beta-blockers are usually linked to weight gain (about 1.2 kg on average), followed by a plateau.