Is taking Klonopin while pregnant safe?
In general, using Klonopin while you are pregnant should be avoided. However, this may be difficult for some women who need the medication to function in their daily lives. If you are currently using Klonopin and become pregnant, do not adjust your treatment schedule before speaking with your doctor.
What fetal risks are related to maternal benzodiazepine use during pregnancy?
A recent study conducted by the Yale University School of Medicine found that pregnancies with maternal use of benzodiazepines are 2.5 times more likely to result in cesarean delivery (C-section birth) and almost 3 times more likely to result in a need for ventilatory support for the newborn baby.
What is the safest benzodiazepine during pregnancy?
The available literature suggests that it is safe to take diazepam during pregnancy but not during lactation because it can cause lethargy, sedation, and weight loss in infants. The use of chlordiazepoxide during pregnancy and lactation seems to be safe.
Is clozapine safe during pregnancy?
In treating women who have become pregnant, the minimal effective dose of clozapine should be used; both increased and decreased dose requirements during pregnancy have been described. Clozapine may also increase the risk of developing gestational diabetes.
What pregnancy category is clozapine?
Safety of Psychiatric Medications During Pregnancy and Lactation
| Drug | FDA pregnancy category* |
|---|---|
| Antipsychotics | |
| Aripiprazole (Abilify) | C |
| Chlorpromazine (Thorazine)‡ | C |
| Clozapine (Clozaril) | B |
What does clozapine do to the body?
Clozapine is a psychiatric medication (anti-psychotic type) that works by helping to restore the balance of certain natural substances (neurotransmitters) in the brain. Clozapine decreases hallucinations and helps prevent suicide in people who are likely to try to harm themselves.
Is there an alternative to clozapine?
Loxapine can be an excellent alternative to clozapine. It is comparable to clozapine in efficacy, cost-effectiveness, and a better side effect profile with more administration routes.
Is clozapine a good drug?
Clozapine has an average rating of 7.8 out of 10 from a total of 54 ratings on Drugs.com. 70% of users who reviewed this medication reported a positive effect, while 19% reported a negative effect.
What is the most serious side effect of clozapine?
Clozapine can cause serious heart problems. Call your doctor right away if you have chest pain, trouble breathing, fast or pounding heartbeats or sudden dizziness.
Does clozapine affect memory?
Clozapine is an effective antipsychotic drug, but its effects on cognitive function are unclear. Previously, we found that clozapine caused a working memory deficit, which was reversed by nicotine. Hippocampal systems are important in determining clozapine effect on memory.
Is clozapine hard on the kidneys?
Clozapine-associated renal failure is a rare complication of clozapine treatment that can have significant impact on quality of life. This case contributes to the literature on this important adverse effect and highlights the need for early diagnosis.
What happens if I stop taking clozapine?
Rapid discontinuation of clozapine has been reported to cause rebound psychosis and worsening of symptoms within 24 to 48 hours of drug cessation.
How much clozapine is too much?
Merz, the UK manufacturer of Denzapine, also advises the prescription of clozapine at a dose between 200 mg/day and 450 mg/day, with maximum doses up to 900 mg/day.
How much clozapine is safe?
Clonazepam dosage However, the maximum dosage does not usually exceed 4 mg per day. For seizures, the dosage for adults is 0.5 mg three times per day. A doctor can increase the dosage in increments of 0.5 mg to 1 mg until the seizures are under control. The maximum dosage should not exceed 20 mg per day.