What happens in sleeping sickness?
Fever, severe headaches, irritability, extreme fatigue, swollen lymph nodes, and aching muscles and joints are common symptoms of sleeping sickness. Some people develop a skin rash. Progressive confusion, personality changes, and other neurologic problems occur after infection has invaded the central nervous system.
What are the complications of trypanosomiasis?
Complications of African trypanosomiasis may include the following:
- Anemia and fatigue.
- Wasting syndrome.
- Aspiration pneumonia.
- Meningoencephalitis and seizures.
- Stupor or coma (sleeping sickness)
- Death.
- Perinatal death or abortion (after congenital infection)
What is the treatment of trypanosomiasis?
The acute phase of trypanosomiasis (Chagas disease) is treated with nifurtimox or benznidazole. Cases of congenital Chagas disease have been successfully treated with either drug. A single case of successful treatment of an adult with posaconazole (after failure of therapy with benznidazole) has been reported.
What are the prevention of trypanosomiasis?
There is no vaccine or drug for prophylaxis against African trypanosomiasis. Preventive measures are aimed at minimizing contact with tsetse flies. Local residents in endemic countries are usually aware of the areas that are heavily infested and may be able to provide advice about places to avoid.
How do you control nagana?
If detected early, Trypanosomosis can be treated with trypanocidal drugs for therapeutic and prophylactic purposes. Therapeutic drugs for cattle include diminazene aceturate, homidium chloride and homidium bromide. Prophylactic drugs for cattle include homidium chloride, homidium bromide and isometamidium.
What is the mode of transmission of sleeping sickness?
Both forms of sleeping sickness are transmitted by the bite of the tsetse fly (Glossina species). Tsetse flies inhabit rural areas, living in the woodlands and thickets that dot the East African savannah. In central and West Africa, they live in the forests and vegetation along streams.