Can interferon cause thyroid problems?

Can interferon cause thyroid problems?

Indeed, thyroid dysfunction is the most common endocrinopathy associated with the IFN-based treatment of HCV infection [7]. Interferon-induced thyroiditis (IIT) is a major clinical problem for patients who receive IFN therapy, with complications like thyrotoxicosis being especially severe [9], [10], [11], [12].

Can HCV cause hyperthyroidism?

Hepatitis C and Thyroid Hormone Levels Thyroid hormone levels can be affected by hepatitis. Chronic hepatitis C is associated with a hypothyroidism, which is underactive thyroid function. 2 It has not been associated with hyperthyroidism, which is overactive thyroid function.

Can immunotherapy cause hyperthyroidism?

Hyperthyroidism developed in 2% of patients during immunotherapy and 6% after. Thyroid dysfunction was not a function of sex, diagnosis, type of treatment, or response to immunotherapy.

Can Hep C cause thyroid nodules?

Among the endocrine disorders, thyroid problems are the most common and the thyroid is one of the principal target organs for extrahepatic manifestations in HCV infected patients. In addition, research data suggest that interferon treatment may be associated with immune-mediated thyroid lesions.

Does Hep C affect gallbladder?

Some people with hepatitis C develop problems with their gallbladder, particularly in those with more severe liver disease. This can lead to inflammation and pain causing nausea and possibly vomiting. It may also cause difficulty when eating certain foods, especially fatty foods.

Can thyroid cause liver problems?

Liver diseases are also frequently associated with thyroid test abnormalities or dysfunctions, particularly elevation of thyroxine-binding globulin and thyroxine. Hepatitis C virus infection has been connected with thyroid abnormalities.

Can thyroid problems cause jaundice?

Jaundice in patients with thyrotoxicosis could be due to the thyrotoxicosis itself, could be as a result of drug treatment of the thyrotoxicosis, could be due to conditions associated with autoimmune thyroid disease like autoimmune hepatitis or could be due to unrelated conditions like sepsis or viral hepatitis.

How does hypothyroidism cause jaundice?

Congenital hypothyroidism: Hypothyroidism causes decreased rate of bilirubin conjugation, slows gut motility and impairs feeding, all contributing to jaundice.

Does thyroid affect cholesterol?

Even people with mildly low thyroid levels, called subclinical hypothyroidism, can have higher than normal LDL cholesterol. A 2012 study found that high TSH levels alone can directly raise cholesterol levels, even if thyroid hormone levels aren’t low. Hyperthyroidism has the opposite effect on cholesterol.

Does thyroid affect blood sugar?

Thyroid Disease and Blood Sugar Your thyroid gland and thyroid hormones play a major role in regulating many of your body’s biological processes, such as growth, development, and metabolism. 2 Because thyroid disease interferes with metabolism, it can alter your blood sugar.

Does low thyroid cause high blood sugar?

Hypothyroidism causes many metabolic abnormalities as well as multiple clinical symptoms. Some studies suggest that blood sugar may be affected in hypothyroidism and levels may increase. Indeed, it has been noted that patients with diabetes who also have hypothyroidism may have higher levels of Hemoglobin A1C (HBA1C).

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