Is Hep B DNA or RNA virus?
HBV, a member of the Hepadnaviridae family, is a small DNA virus with unusual features similar to retroviruses. HBV replicates through an RNA intermediate and can integrate into the host genome.
Why is hep B partially double stranded?
Hepatitis B virus assembly begins with the packaging of an RNA pregenome into intracellular nucleocapsids, with subsequent reverse transcription within these nucleocapsids converting the RNA into a characteristic, partially double-stranded DNA, which, alone, is found in enveloped extracellular virions as the viral …
Does Hepatitis B contain different strands?
Hepatitis B virus (HBV) is a para-retrovirus or retroid virus that contains a double-stranded DNA genome and replicates this DNA via reverse transcription of a RNA pregenome.
Is hepatitis B single stranded?
2 HBV genome organisation. The HBV genome is made up of a circular DNA which is partly single stranded and partly double stranded.
Which is the correct statement related to hepatitis B virus?
Despite there being a vaccine to prevent Hepatitis B, HBV remains a global health problem. Hepatitis B can be acute and later become chronic, leading to other diseases and health conditions. In addition to causing hepatitis, infection with HBV can lead to cirrhosis and hepatocellular carcinoma.
Who identify the hepatitis B virus?
The hepatitis B virus was discovered in 1965 by Dr. Baruch Blumberg who won the Nobel Prize for his discovery. Originally, the virus was called the “Australia Antigen” because it was named for an Australian aborigine’s blood sample that reacted with an antibody in the serum of an American hemophilia patient.
What is the hepatitis B surface antibody?
The hepatitis B surface antibody (anti-HBs) is the antibody that is produced in response to hepatitis B surface antigen (HbsAg), a protein present on the surface of the hepatitis B virus. Anti-HBs appears after convalescence from acute infection and lasts for many years.
Is hepatitis B contagious forever?
Symptoms of hepatitis B may not appear for 3 months after exposure and can last for 2–12 weeks. However, you are still contagious, even without symptoms . The virus can live outside the body for up to seven days.
How common is a false positive hep B test?
Results and Discussion During the first month of program initiation, the administration of hepatitis B vaccine and the test for HBsAg were performed simultaneously. The lab reported three cases of HBsAg positivity, and informed the clinicians, the false positive result turned out to be 2.56%.