What causes IgA to drop?
Autoimmune diseases, in which your immune system attacks particular organs or tissues in your own body, can be found with selective IgA deficiency. Common autoimmune conditions found with IgA deficiency include rheumatoid arthritis, lupus, celiac disease or inflammatory bowel disease.
What does a low IgA indicate?
Some people with an IgA deficiency are more likely to get frequent infections. These can include sinus, lung, and digestive infections. Some people with IgA deficiency also are more likely to have allergies, and digestive and autoimmune problems such as celiac disease or lupus.
Is IgA deficiency serious?
For some with IgA deficiency, the condition is ‘silent,’ meaning they no symptoms, however for others it is associated with a heightened risk of infections, allergies, asthma and autoimmune diseases. Some affected by IgA deficiency face serious health issues such as chronic infections or diarrhea.
Does IgA deficiency make you immunocompromised?
Selective IgA deficiency is the most common primary immunodeficiency disease (PIDD). People with this disorder have absent levels of a blood protein called immunoglobulin A (IgA). IgA protects against infections of the mucous membranes lining the mouth, airways and digestive tract.
What is the prognosis of celiac disease?
Without diagnosis and treatment, celiac disease is ultimately fatal in 10 to 30% of people. Currently this outcome is rare, as most people do well if they avoid gluten. Following a gluten-free diet heals the damage to the intestines and prevents further damage.
Can you suddenly become celiac?
Celiac disease can develop at any age after people start eating foods or medications that contain gluten. The later the age of celiac disease diagnosis, the greater the chance of developing another autoimmune disorder. There are two steps to being diagnosed with celiac disease: the blood test and the endoscopy.
What are the long-term effects of celiac disease?
Long-Term Health Conditions
- Iron deficiency anemia.
- Early onset osteoporosis or osteopenia.
- Infertility and miscarriage.
- Lactose intolerance.
- Vitamin and mineral deficiencies.
- Central and peripheral nervous system disorders.
- Pancreatic insufficiency.
- Intestinal lymphomas and other GI cancers (malignancies)