What does hemophilia mean?

What does hemophilia mean?

Hemophilia is usually an inherited bleeding disorder in which the blood does not clot properly. This can lead to spontaneous bleeding as well as bleeding following injuries or surgery. Blood contains many proteins called clotting factors that can help to stop bleeding.

What is the best definition of haemophilia?

: a tendency to uncontrollable bleeding especially : a hereditary, sex-linked blood disorder occurring almost exclusively in males that is marked by delayed clotting of the blood with prolonged or excessive internal or external bleeding after injury or surgery and in severe cases spontaneous bleeding into joints and …

Is Hemophilia a real word?

Hemophilia is a genetic disorder that makes it hard for a person’s blood to clot. People with hemophilia are at risk of bleeding a lot even from minor injuries. Men are much more likely than women to suffer from hemophilia.

How can a person get hemophilia?

Hemophilia is an inherited genetic condition, meaning it is passed down through families. It’s caused by a defect in the gene that determines how the body makes factors VIII, IX, or XI. These genes are located on the X chromosome, making hemophilia an X-linked recessive disease.

What are the 2 types of hemophilia?

The two most common types of hemophilia are factor VIII deficiency (hemophilia A) and factor IX deficiency (hemophilia B, or Christmas disease).

Should you breed a dog with von Willebrand disease?

If you plan to breed your dog, a VWD screening should be done beforehand. Even if a pet doesn’t have any symptoms it may have VWD, or it could be a carrier. If the test indicates your dog has VWD or is a carrier, it certainly should not be bred with another animal with VWD, and many vets advise not breeding it at all.

Is desmopressin the same as vasopressin?

Desmopressin, a synthetic form of the human hormone vasopressin, limits the amount of water eliminated in the urine. It can be administered nasally, via IV, orally, or given as a sublingual tablet. Major uses of desmopressin include bed-wetting, nighttime urination, clotting disorders, and diabetes insipidus.

Does Ddavp increase platelets?

We show that in vivo DDAVP selectively and markedly enhances the ability to form procoagulant platelets and increases platelet-dependent thrombin generation by enhancing Na(+)/Ca(2+) mobilization. This report indicates that the beneficial hemostatic effect of DDAVP is not limited to an increase in large VWF multimers.

What is the purpose of desmopressin?

Desmopressin is used to control the symptoms of a certain type of diabetes insipidus (‘water diabetes’; condition in which the body produces an abnormally large amount of urine).

How effective is desmopressin?

One randomized controlled trial found a linear dose response for oral desmopressin in reducing wet nights. After 2 weeks of treatment, the number of wet nights was decreased by 27%, 30%, and 40% at doses of 0.2 mg, 0.4 mg, and 0.6 mg, respectively, compared with 10% with placebo.

How does desmopressin work in the body?

Desmopressin works by reducing the amount of urine produced in the body at night by the kidneys. This means that the bladder then fills with less urine during the night. Desmopressin is usually taken at bedtime.

Can desmopressin cause weight gain?

Desmopressin can sometimes cause fluid retention. Early symptoms are swelling of the face, hands or feet, bad or prolonged headaches, drowsiness (feeling sleepy), unexplained weight gain, feeling sick (nausea) and being sick (vomiting).

Does desmopressin cause mood swings?

mental/mood changes (confusion, hallucinations, irritability), loss of consciousness, seizures, or. slow/shallow breathing.

How long can you take desmopressin for?

Desmopressin can be taken regularly every night or just for one-off occasions. Your child would need to try it before the occasion to work out the right dose and make sure it helps them to be dry. To start with however, it is recommended that it is taken for a minimum of three months without a break.

What drugs interact with desmopressin?

View interaction reports for desmopressin and the medicines listed below.

• Abilify (aripiprazole)
• Adderall (amphetamine / dextroamphetamine)
• Aspirin Low Strength (aspirin)
• Benadryl (diphenhydramine)
• Fish Oil (omega-3 polyunsaturated fatty acids)
• Keppra (levetiracetam)
• Lamictal (lamotrigine)
• Lexapro (escitalopram)

Is there an alternative to desmopressin?

Alternatives to desmopressin as pharmacologic therapy for DI include synthetic vasopressin and the nonhormonal agents chlorpropamide, carbamazepine, clofibrate (no longer on the US market), thiazides, and nonsteroidal anti-inflammatory drugs (NSAIDs).