What genetic disorder only affects males?

What genetic disorder only affects males?

Affected Populations XYY syndrome is a rare chromosomal disorder present at birth that affects only males. It is estimated to occur in approximately one in 1,000 live births.

What is single gene inheritance?

Remember, for any given gene, a person inherits one allele from his or her mother and one allele from his or her father. Therefore, individuals with an autosomal recessive single-gene disease inherit one mutant allele of the disease-associated gene from each of their parents.

How common is single gene disorder?

The mutated version of the gene responsible for the disorder is known as a mutant, or disease, allele?. Individually, single gene disorders are each very rare, but as a whole, they affect about one per cent of the population.

What is the most common single gene disorder?

Some of the more common single-gene disorders include cystic fibrosis, hemochromatosis, Tay-Sachs, and sickle cell anemia. Even though these diseases are primarily caused by a single gene, several different mutations can result in the same disease but with varying degrees of severity and phenotype.

How do single gene disorders occur?

Single-gene disorder is a disease caused by a known alteration or mutation in one of more than 20.000 genes in nearly every cell in the body. Single-gene disorder may be inherited from both members of a couple carry the same condition. It can also be inherited through one or more generations in the family.

Is there a cure for single gene disorders?

Many genetic disorders result from gene changes that are present in essentially every cell in the body. As a result, these disorders often affect many body systems, and most cannot be cured.

Is cystic fibrosis caused by a single gene?

Every person has two copies of the cystic fibrosis transmembrane conductance regulator (CFTR) gene. A person must inherit two copies of the CFTR gene that contain mutations — one copy from each parent — to have cystic fibrosis. Some genetic diseases, such as cystic fibrosis, are caused by mutations in a single gene.