What is broad to narrow?
2. In this context “broad” means generally applicable and with wide (lots of) applications. Examples for broad traits might be “being a good communicator”, “being good with numbers”, “being tolerant”, “keeping situational awareness” By contrast “narrow”, here, means a very specific skill with limited applicability
What is the difference between broad and narrow spectrum antibiotics?
Narrow-spectrum antibiotics target a few types of bacteria. Broad-spectrum antibiotics target many types of bacteria. Both types work well to treat infections. But using broad-spectrum antibiotics when they’re not needed can create antibiotic-resistant bacteria that are hard to treat
What would a narrow spectrum antibiotic be?
Examples of narrow-spectrum antibiotics are the older penicillins (penG), the macrolides and vancomycin. Examples of broad-spectrum antibiotics are the aminoglycosides, the 2nd and 3rd generation cephalosporins, the quinolones and some synthetic penicillins.
Is amoxicillin broad or narrow?
For example, AAP guidelines recommend amoxicillin, a narrow-spectrum drug, as a first-line treatment for acute sinusitis, but the Infectious Diseases Society of America endorses amoxicillin-clavulanate, a broad-spectrum medication
Why is it better to use narrow spectrum antibiotics?
Advantages. Narrow-spectrum antibiotic allow to kill or inhibit only those bacteria species that are unwanted (i.e. causing disease). As such, it leaves most of the beneficial bacteria unaffected, hence minimizing the collateral damage on the microbiota. Low propensity for bacterial resistance development.
Which is better broad-spectrum or narrow spectrum?
Narrow-spectrum antibiotics are only effective against a narrow range of bacteria, but broad-spectrum antibiotics are effective against a broad range of bacteria. It’s a good idea to use narrow-spectrum antibiotics when possible, because they won’t kill the patient’s ‘good’ bacteria and cause opportunistic infections.
Are glycopeptides broad or narrow spectrum?
Narrow spectrum antibacterials have limited activity and are primarily only useful against particular species of microorganisms. For example, glycopeptides and bacitracin are only effective against Gram-positive bacteria, whereas polymixins are usually only effective against Gram negative bacteria.
Is rifampin broad or narrow spectrum?
Rifampin is one of the most potent and broad-spectrum antibiotics against bacterial pathogens. Its bactericidal activity is due to its ability to bind to the β subunit of the DNA-dependent RNA polymerase encoded by the rpoB gene.
What is the most common side effect of rifampin?
Upset stomach, heartburn, nausea, menstrual changes, or headache may occur. If any of these effects persist or worsen, inform your doctor promptly. This medication may cause urine, sweat, saliva, or tears to change color (yellow, orange, red, or brown).
Is ciprofloxacin broad or narrow spectrum?
Some antibiotics are more specific (narrow-spectrum) and some kill a wider range of bacteria (broad-spectrum). Ciprofloxacin is a broad-spectrum antibiotic that was once used to treat a wide range of infections, especially respiratory and urinary tract infections.
Is clindamycin broad or narrow spectrum?
Clindamycin is a broad spectrum antibiotic used orally, topically and parenterally for bacterial infections due to sensitive organisms.
Are penicillins broad or narrow spectrum?
In all of our analyses, we examine the use of narrow-spectrum antibiotics as well as broad-spectrum antibiotics, which have greater implications for the spread of antibiotic-resistant infections….Table 1.
| Type of Antibiotic | Penicillin | |
|---|---|---|
| Any Antibiotic | 16.9 (0.3) | |
| Spectrum | Broad | 2.7 (0.1) |
| Narrow | 15.1 (0.3) | |
What bacteria does clindamycin kill?
Effective against a number of different gram positive and anaerobic bacteria, including susceptible strains of Staphylococcus aureus (methicillin-susceptible strains only), Streptococcus pneumoniae (penicillin-susceptible strains only), S. pyogenes, Clostridium perfringens, Fusobacterium necrophorum, F
Is metronidazole broad or narrow spectrum?
Flagyl, known generically as metronidazole or by the brand name Protostat, is an antibacterial drug that is classified as a broad-spectrum antibiotic. 1 Metronidazole is used to treat anaerobic bacterial infections or protozoal infections.
What does it mean if there is no zone of inhibition?
A lack of visual zone does not mean the antimicrobial agent is ineffective: the zone of inhibition test requires the antimicrobial agent to migrate into the nutrient agar. If the antimicrobial is not compatible with the nutrient agar, it will not migrate to create a visual zone of inhibition.
What kind of antibiotic is metronidazole?
Metronidazole is a commonly used antibiotic, belonging to the nitroimidazole class of antibiotics. It is frequently used to treat gastrointestinal infections as well as trichomoniasis and giardiasis, and amebiasis which are parasitic infections.
Are metronidazole and amoxicillin the same?
Metronidazole is an alternative to amoxicillin for the treatment of some oral infections
Why do I need amoxicillin and metronidazole?
A combination of metronidazole (MET) and amoxicillin (AMX) is commonly used as adjunct to mechanical therapy of periodontal disease. The use of broad spectrum antibiotics such as AMX may contribute to development of antibiotic resistance
What should I avoid while taking metronidazole?
Do not drink alcohol or consume food or medicines that contain propylene glycol while you are taking metronidazole. You may have unpleasant side effects such as headaches, stomach cramps, nausea, vomiting, and flushing (warmth, redness, or tingly feeling).
What bacteria does metronidazole kill?
Metronidazole has activity against protozoans like Entamoeba histolytica, Giardia lamblia and Trichomonas vaginalis, for which the drug was first approved as an effective treatment. Anaerobic bacteria which are typically sensitive are primarily Gram-negative anaerobes belonging to the Bacteroides and Fusobacterium spp.
How long is metronidazole good for?
Most courses of metronidazole last for around seven days, but some may be as short as three days and some as long as 14 days. For certain infections you may be given a single, larger dose of metronidazole, usually five 400 mg tablets (2 g) to take at once
What is metronidazole commonly used to treat?
Metronidazole is an antibiotic. It’s used to treat skin infections, rosacea and mouth infections (including infected gums and dental abscesses). It’s used in the treatment of conditions such as bacterial vaginosis and pelvic inflammatory disease.
What’s the side effects of metronidazole?
Dizziness, headache, stomach upset, nausea, vomiting, loss of appetite, diarrhea, constipation, or metallic taste in your mouth may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly. This medication may cause your urine to turn darker in color.