What is the composition of grapefruit?
Fresh Fruit
| Chemical composition | Pulp (raw) | Juice (raw) |
|---|---|---|
| protein | 0.5–1.0 g | 0.4–0.5 g |
| Fat | 0.06–0.20 g | 0.1 g |
| Carbohydrates | 8.07–11.5 g | 8.8–10.2 g |
| Fiber | 0.14–0.77 g | trace |
Is grapefruit juice an inducer or inhibitor?
Grapefruit juice, a beverage consumed in large quantities by the general population, is an inhibitor of the intestinal cytochrome P-450 3A4 system, which is responsible for the first-pass metabolism of many medications.
What enzyme is in grapefruit?
Mechanism. Organic compounds that are derivatives of furanocoumarin interfere with liver and intestinal enzyme CYP3A4 and are believed to be primarily responsible for the effects of grapefruit on the enzyme. Cytochrome isoforms affected by grapefruit components also include CYP1A2, CYP2C9, and CYP2D6.
What does grapefruit juice do to drug metabolism?
Many drugs are broken down (metabolized) with the help of a vital enzyme called CYP3A4 in the small intestine. Grapefruit juice can block the action of intestinal CYP3A4, so instead of being metabolized, more of the drug enters the blood and stays in the body longer. The result: too much drug in your body.
What are the benefits of eating grapefruit?
Here are 10 evidence-based health benefits of grapefruit.
- It’s Low in Calories, Yet High in Nutrients.
- It May Benefit Your Immune System.
- May Promote Appetite Control.
- It Has Been Shown to Aid Weight Loss.
- Grapefruit May Help Prevent Insulin Resistance and Diabetes.
- Eating Grapefruit May Improve Heart Health.
Does grapefruit juice interfere with vitamins?
Dear S.M.: There is no evidence that vitamin or mineral supplements are affected by grapefruit juice in the same way it affects certain medications.
What supplements does grapefruit interfere with?
Some sedative medications (benzodiazepines) that might interact with grapefruit juice include diazepam (Valium), midazolam (Versed), quazepam (Doral), and triazolam (Halcion). The body breaks down sildenafil (Viagra) to get rid of it. Grapefruit can decrease how quickly the body breaks down sildenafil (Viagra).
Which is healthier orange juice or grapefruit juice?
Orange juice contains almost three times as much folate as grapefruit juice — 74 micrograms per cup, compared to 25 micrograms in grapefruit juice. Each cup of orange juice provides 19 percent of your daily recommended intake of folate, according to the NYU Langone Medical Center.