What is the initiator protein in DNA replication?
The initiator proteins are the proteins that recognize a specific DNA sequence within the origin of replication. The origin of replication is the site where the helicase attaches to the template strand and starts to unwind the DNA into two strands.
What does DnaA stand for?
DNAA
| Acronym | Definition |
|---|---|
| DNAA | Delayed Neutron Activation Analysis |
| DNAA | Durham and Northumberland Archery Association (UK) |
| DNAA | Driffield Navigation Amenities Association (UK) |
| DNAA | Defective DNA of the Bacteria Escherichia Coli |
What is the function of DnaC?
The dnaC protein of Escherichia coli, by forming a complex with the dnaB protein, facilitates the interactions with single-stranded DNA that enable dnaB to perform its ATPase, helicase, and priming functions.
What is DnaA box?
Abstract. The binding of DnaA protein to its DNA binding sites—DnaA boxes—in the chromosomal oriC region is essential for initiation of chromosome replication. In this report, we show that additional DnaA boxes affect chromosome initiation control, i.e., increase the initiation mass.
What is at rich region?
The opening creates a single-stranded DNA (ssDNA) which is indispensable for the replication initiation of a double-stranded (dsDNA) replicon. The AT-rich region is exactly the site where a replication complex is formed and where the DNA synthesis is initiated.
What is DnaA DnaB and DnaC?
DnaA and DnaC are specifically required at the stage of initiation of DNA replication from the E. coli replication origin (oriC) to load the replicative DNA helicase (DnaB) at this chromosomal site. DnaA is a protein that binds ATP and also DNA, but in a sequence-specific manner.
Is Primase a protein?
Archaeal and eukaryote primases are heterodimeric proteins with one large regulatory and one small catalytic subunit. The RNA segments are first synthesized by primase and then elongated by DNA polymerase.
What is the difference between DNA replication in leading and lagging strand?
The main difference between leading and lagging strand is that the leading strand is the DNA strand, which grows continuously during DNA replication whereas lagging strand is the DNA strand, which grows discontinuously by forming short segments known as Okazaki fragments.
Which enzyme is responsible for assembling the DNA double helix?
DNA polymerase