What is the strand that is copied in a continuous way from the 3 to 5 direction?
When replication begins, the two parent DNA strands are separated. One of these is called the leading strand, and it is replicated continuously in the 3′ to 5′ direction. The other strand is the lagging strand, and it is replicated discontinuously in short sections.
Is the lagging strand continuous?
This enzyme can work only in the 5′ to 3′ direction, so it replicates the leading strand continuously. Lagging-strand replication is discontinuous, with short Okazaki fragments being formed and later linked together.
Why is the lagging strand discontinuous?
On the upper lagging strand, synthesis is discontinuous, since new RNA primers must be added as opening of the replication fork continues to expose new template. This produces a series of disconnected Okazaki fragments.
Why is DNA replication continuous for one strand but discontinuous for the other?
One new strand, which runs 5′ to 3′ towards the replication fork, is the easy one. This strand is made continuously, because the DNA polymerase is moving in the same direction as the replication fork.
What are the three major requirements of replication?
What are three major requirements of replication? A single-stranded template, raw materials (nucleotides, sugars, phosphates), enzymes and proteins to read the template and assemble the new strand.
In what direction are Okazaki fragments synthesized?
Okazaki Fragments. At a replication fork, both strands are synthesized in a 5′ → 3′ direction. The leading strand is synthesized continuously, whereas the lagging strand is synthesized in short pieces termed Okazaki fragments.
What enzyme unwinds the DNA?
DNA helicases
What is the enzyme that unzips the DNA strand?
helicases
What is 3 end DNA?
3. Each DNA strand has two ends. The 5′ end of the DNA is the one with the terminal phosphate group on the 5′ carbon of the deoxyribose; the 3′ end is the one with a terminal hydroxyl (OH) group on the deoxyribose of the 3′ carbon of the deoxyribose.