What virus did Hershey and Chase use?
In 1952, Alfred Hershey and Martha Chase published a convincing demonstration that DNA (not protein) was the genetic material. The Hershey–Chase experiment was carried out with a virus, called bacteriophage T2, that infects bacteria. Bacteriophage T2 consists of little more than a DNA core packed inside a protein coat.
What part of the bacteriophage is actually inserted into E coli?
the DNA component of the bacteriophages is injected into the bacterial cell while the protein component remains outside. However, it is the injected component — DNA — that is able to direct the formation of new virus particles complete with protein coats.
How did Hershey and Chase know that it was infected with DNA?
How did Hershey and Chase know that it was the DNA that had infected the bacterial cells in their experiment? the harmless bacteria would be transformed into disease causing bacteria. to test this hypothesis, he could inject the bacteria into the mice and see if the mice develops pneumonia.
What bacteria killed the mice?
Pneumococcus bacteria include two strains, a virulent S strain with a Smooth glycoprotein coat that kills mice (left), and a non-virulent R Rough strain that does not (middle). Heating destroys the virulence of S (right).
What happened when Griffith injected mice with R strain bacteria alone?
2-What happened when Griffith injected mice with the harmless, R-strain bacteria alone? harmless bacteria into mice? THE MICE DEVELOPED PNEUMONIA. 4-What did Avery conclude caused transformation?
How did Griffith determine which strain caused disease?
Griffith concluded that something had passed from the heat-killed S strain into the live R strain and transformed it into the pathogenic S strain. He called this the transforming principle (Figure 2). These experiments are now known as Griffith’s transformation experiments.
How did the two types of bacteria used by Griffith differ?
The bacteriologists were interested in the difference between two strains of Streptococci that Frederick Griffith had identified in 1923: one, the S (smooth) strain, has a polysaccharide coat and produces smooth, shiny colonies on a lab plate; the other, the R (rough) strain, lacks the coat and produces colonies that …