Who should not take carbamazepine?
You should not take carbamazepine if you have a history of bone marrow suppression, or if you are allergic to carbamazepine or to an antidepressant such as amitriptyline, desipramine, doxepin, imipramine, or nortriptyline. Do not use carbamazepine if you have taken an MAO inhibitor in the past 14 days.
What medications make glaucoma worse?
The classes of medications that have the potential to induce angle closure are topical anticholinergic or sympathomimetic dilating drops, tricyclic antidepressants, monoamine oxidase inhibitors, antihistamines, antiparkinsonian drugs, antipsychotic medications, and antispasmolytic agents.
Does carbamazepine lower your immune system?
Results of clinical studies indicate that phenytoin, carbamazepine, and valproate, show immunosuppressive activity, inhibit protein synthesis in lymphocytes, decrease CD4+/CD8+ ratio, decrease IgA, and induce changes in IgG and IgM plasma levels.
Can you take vitamin D with carbamazepine?
carBAMazepine cholecalciferol Using carBAMazepine together with cholecalciferol may decrease the effects of cholecalciferol. Contact your doctor if your condition changes. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications.
Can carbamazepine cause vitamin deficiency?
Individuals on long-term multiple anticonvulsant therapy may develop below-normal blood levels of calcium, which may be related to drug-induced vitamin D deficiency.
Does carbamazepine affect memory?
Conclusions. In TLE patients, carbamazepine reduces the fMRI-detectable changes within the mesial temporal lobes as induced by effortful memory retrieval. FMRI appears to be suitable to study the effects of chronic drug treatment in patients with epilepsy.
Does carbamazepine make you gain weight?
Lithium, valproic acid (Depakote) and carbamazepine (Tegretol) can also put on the pounds. Drugs with hormonal effects, such as antipsychotics and steroids, are among the biggest culprits in weight gain, Cheskin said. “They work on the brain, and appetite control is largely a brain function.
Does carbamazepine cause hair loss?
Carbamazepine therapy can also cause hair loss. This drug-induced alopecia may be noted in less than 1 of 1000 persons treated (1 1).
How long does carbamazepine stay in system?
After single oral doses of carbamazepine, the absorption is fairly complete and the elimination half-life is about 35 hours (range 18 to 65 hours). During multiple dosing, the half-life is decreased to 10-20 hours, probably due to autoinduction of the oxidative metabolism of the drug.
Does carbamazepine cause liver damage?
Carbamazepine is an aromatic anticonvulsant that is widely used in therapy of epilepsy and trigeminal neuralgia and is a well established cause of clinically apparent liver injury which can be severe and even fatal.
Can I drink alcohol while taking carbamazepine?
carBAMazepine food You should avoid or limit the use of alcohol while being treated with carBAMazepine. Alcohol can increase the nervous system side effects of carBAMazepine such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment.
Can you have a glass of wine while taking carbamazepine?
You should avoid or limit the use of alcohol while being treated with carBAMazepine. Alcohol can increase the nervous system side effects of carBAMazepine such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment.
What drugs does carbamazepine interact with?
Examples of affected drugs include artemether/lumefantrine, boceprevir, certain drugs used to prevent blood clots (anticoagulants such as apixaban, rivaroxaban), certain calcium channel blockers (such as nifedipine, nimodipine), nefazodone, HIV NNRTIs (such as delavirdine, efavirenz, etravirine, rilpivirine).
Can I eat grapefruit while taking carbamazepine?
Grapefruit and grapefruit juice may increase the effects of this medicine by increasing the amount in the body. You should not eat grapefruit or drink grapefruit juice while you are taking this medicine. If you are taking this medicine for pain relief: Carbamazepine is not an ordinary pain reliever.
What does grapefruit do to carbamazepine?
Conclusion: Grapefruit juice increases the bioavailability of carbamazepine by inhibiting CYP3A4 enzymes in gut wall and in the liver.