Does grapefruit affect hydrochlorothiazide?
Grapefruit juice can significantly increase the blood levels and effects of medications like felodipine. You may be more likely to experience side effects such as headache, low blood pressure, irregular heartbeat, swelling, and fluid retention.
What medications should not be taken with hydrochlorothiazide?
Hydrochlorothiazide may interact with other medications
- Barbiturates. If you take these drugs with hydrochlorothiazide, your blood pressure may be lowered too much.
- Lithium.
- Blood pressure drugs.
- Cholesterol-lowering drugs.
- Corticosteroids.
- Diabetes drugs.
- Narcotics.
- Nonsteroidal anti-inflammatory drugs (NSAIDs)
Should I drink more water when taking hydrochlorothiazide?
Be careful not to become overheated or dehydrated in hot weather while taking hydrochlorothiazide. Talk to your doctor about how much fluid you should be drinking; in some cases drinking too much fluid is just as harmful as not drinking enough fluids.
Is 50 mg of hydrochlorothiazide too much?
Adults—At first, 12.5 milligrams (mg) or one capsule once a day. Your doctor may want you to take this alone or together with other blood pressure medicines. Your doctor may increase your dose as needed. However, the dose is usually not more than 50 mg per day.
How much weight can you lose with hydrochlorothiazide?
The effective dose of hydrochlorothiazide in 52% of these responders was 50 mg/day, and this was associated with weight loss averaging 1.58 kg. An additional 29% achieved goal BP with a similar degree of weight loss, but they required double the dose, or 100 mg/day.
Can I drink any alcohol at all while taking hydrochlorothiazide?
Notes for Consumers: It is best to limit your intake of alcohol while taking this drug. Alcohol can increase the risk for low blood pressure and dizziness. If the blood pressure drops too low, you may feel dizzy or faint, in some cases falls or fainting may occur.
Is it OK to just stop taking hydrochlorothiazide?
Do not stop using hydrochlorothiazide and metoprolol suddenly, even if you feel fine. Stopping suddenly may cause serious or life-threatening heart problems. Follow your doctor’s instructions about tapering your dose.
Can you lose weight on hydrochlorothiazide?
Does hydrochlorothiazide (Microzide) cause weight loss? Hydrochlorothiazide (Microzide) works to get rid of extra fluid in your body. By getting rid of this fluid, it can cause weight loss. Keep in mind that this is water weight, not fat loss.
How long does hydrochlorothiazide 12.5 mg stay in your system?
Official Answer. It takes approximately 3.5 days for hydrochlorothiazide to be removed from the body. Hydrochlorothiazide has an elimination half-life of 6 to 15 hours. The half life is used to estimate how long it takes for a drug to be eliminated from the body.
Can HCTZ cause joint pain?
Taking HCTZ may also lead to gout—a painful type of arthritis characterized by sudden pain, redness, and swelling of the joints—because this medication can cause high uric acid levels (hyperuricemia) (Jin, 2012).
What kind of diuretic is hydrochlorothiazide?
Hydrochlorothiazide is a thiazide diuretic (water pill). It is used to help reduce the amount of water in the body by increasing the flow of urine.
Is 12.5 mg of hydrochlorothiazide effective?
These results suggest that in combination with nadolol, 12.5 mg of hydrochlorothiazide per day has no significant antihypertensive effect. There was no evidence of a flat dose-response curve in the daily dose range of 12.5 to 50 mg.
How long does it take for hydrochlorothiazide to start working?
Pharmacological effects begin in about 2 hours after an oral dose, peaks in 4 hours, and lasts for about 6 to 12 hours. Hydrochlorothiazide is not metabolized, and a majority is excreted in the urine unchanged. It also causes a loss of potassium and bicarbonate.