What cardiac meds interact with grapefruit?
Here are examples of some types of drugs that grapefruit juice can cause problems (interact) with:
- Some statin drugs to lower cholesterol, such as Zocor (simvastatin) and Lipitor (atorvastatin).
- Some drugs that treat high blood pressure, such as Procardia and Adalat CC (both nifedipine).
What medication does grapefruit affect?
Examples of common medications that interact with grapefruit juice include certain statin cholesterol drugs such as atorvastatin (Lipitor), lovastatin, simvastatin (Zocor), felodipine (Plendil) and other calcium channel blockers, clarithromycin (Biaxin), and loratadine (Claritin).
Does grapefruit juice affect blood pressure medicine?
Though grapefruit does not interfere with most blood pressure medications, it can cause a few medications to overcorrect blood pressure.
What is a serious drug interaction?
Clinically significant drug interactions can occur when two or more drugs are taken in combination [2]. Drug-drug interaction is one cause of adverse reactions leading to an increase in risk of hospitalization and added health care costs.
What happens if you have a drug interaction?
Drug interactions may make your drug less effective, cause unexpected side effects, or increase the action of a particular drug. Some drug interactions can even be harmful to you.
How many medications is considered polypharmacy?
Polypharmacy, defined as regular use of at least five medications, is common in older adults and younger at-risk populations and increases the risk of adverse medical outcomes.
Does polypharmacy decrease the risk of drug interactions?
Polypharmacy increases the risk of adverse reactions to medications. The more drugs, the higher the risk of drug interactions. Research has shown that patients taking five to nine medications have a 50% chance of an adverse drug interaction, increasing to 100% when they are taking 20 or more medications.
What are the risks of polypharmacy?
Unfortunately, there are many negative consequences associated with polypharmacy. , Specifically, the burden of taking multiple medications has been associated with greater health care costs and an increased risk of adverse drug events (ADEs), drug-interactions, medication non-adherence, reduced functional capacity and …
Can polypharmacy cause death?
Polypharmacy describes the use of multiple drugs by a single patient to treat one or more conditions. It is most common among elderly patients, ages 65 and over. It is estimated to cause 100,000 deaths per year.