What causes Klinefelter syndrome and Turner syndrome?
Turner syndrome (TS) is caused by having only one X chromosome (X0), and Klinefelter syndrome (KS) by having two X chromosomes and one Y chromosome (XXY).
What is the cause of chromosomal abnormalities in syndromes such as Down’s Turner’s and Klinefelter’s?
Most people are born with two sex chromosomes. Boys inherit the X chromosome from their mothers and the Y chromosome from their fathers. Girls inherit one X chromosome from each parent. In girls who have Turner syndrome, one copy of the X chromosome is missing, partially missing or altered.
What symptom does both Klinefelter’s and Turner’s have in common?
These 2 diseases are the most sex chromosome disorders characterized by one extra X in the SK male (47XXY) and the loss of an X in the girls with ST (45 X). Their common characteristic is the gonadal dysgenesis, which is the main cause of male or female infertility.
What is the chromosome disorder in Down syndrome Klinefelter syndrome and Turner syndrome?
Klinefelter syndrome is a chromosomal condition that affects male physical and cognitive development….Figure 3.
| Karyotype | Phenotype | Reference |
|---|---|---|
| 48,XXY,+21 | Klinefelter/Down Syndrome | Jeanty and Turner, 2009 [43] |
| 48,XXY,+21 | Klinefelter/Down Syndrome | Gerretsen et al, 2009 [23] |
Is Klinefelter syndrome a type of Down syndrome?
In conclusion, Down–Klinefelter’s syndrome is a rare chromosomal abnormality. Patient present with physical characteristics of Down’s syndrome at birth and Klinefelter’s syndrome features at during puberty. It is important to counsel families about recurrence risk for future pregnancies.
What trisomies are compatible with life?
Human trisomy The most common types of autosomal trisomy that survive to birth in humans are: Trisomy 21 (Down syndrome) Trisomy 18 (Edwards syndrome) Trisomy 13 (Patau syndrome)
Is there a cure for chromosomal abnormalities?
In many cases, there is no treatment or cure for chromosomal abnormalities. However, genetic counseling, occupational therapy, physical therapy and medicines may be recommended.
What is the main cause of chromosomal abnormalities?
Chromosome abnormalities often happen due to one or more of these: Errors during dividing of sex cells (meiosis) Errors during dividing of other cells (mitosis) Exposure to substances that cause birth defects (teratogens)