What is the most commonly prescribed statin?
Currently, atorvastatin (Lipitor) and rosuvastatin (Crestor) are the most potent, and fluvastatin (Lescol) is the least potent. The statins also differ in how strongly they interact with other drugs.
What are the statin drugs names?
They include:
- Atorvastatin (Lipitor)
- Lovastatin (Altoprev)
- Pitavastatin (Livalo, Zypitamag)
- Pravastatin (Pravachol)
- Rosuvastatin (Crestor, Ezallor)
- Simvastatin (Zocor)
What is the strongest statin?
Rosuvastatin and atorvastatin are the strongest statins because they have long half-lives. – Atorvastatin, simvastatin, and lovastatin are metabolized by the P450 cytochrome 3A4, which is inhibited by many other drugs and may thereby increase the risk of myopathy.
What are Dilantin side effects?
Headache, nausea, vomiting, constipation, dizziness, feeling of spinning, drowsiness, trouble sleeping, or nervousness may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. Phenytoin may cause swelling and bleeding of the gums.
Is Dilantin hard on the liver?
Dilantin (phenytoin) can cause liver damage shortly after you start taking it, which is why you will need regular lab tests to monitor your liver functioning. Carbamazepine and lamotrigine can also cause liver injury, which may show up after you’ve been taking either for weeks to months.
Can Dilantin cause eye problems?
Tell your doctor immediately if any of these unlikely but serious side effects occur: unusual eye movements, loss of coordination, slurred speech, confusion, muscle twitching, double or blurred vision, tingling of the hands/feet, facial changes (e.g., swollen lips, butterfly-shaped rash around the nose/cheeks).
Does Dilantin affect blood pressure?
The effect of phenytoin on the cardiovascular system Phenytoin can also cause a lowering in blood pressure as a result of peripheral vasodilatation and negative inotropic effect [32, 33].
How long does Dilantin stay in your system?
The plasma half-life in man after oral administration of phenytoin averages 22 hours, with a range of 7 to 42 hours. Steady-state therapeutic levels are achieved at least 7 to 10 days (5–7 half- lives) after initiation of therapy with recommended doses of 300 mg/day.
How often should a Dilantin level be checked?
A level can be taken 2-4 hours following an IV loading or top-up dose (12-24 hours for oral doses) and levels should then be monitored every 24 hours until control is achieved and concentration has stabilised.
Why do Dilantin levels fluctuate?
But as the concentration rises to therapeutic levels, the enzyme system in the liver can become saturated and elimination occurs at a constant rate despite the dose (zero order kinetics). The effect is that a small increase in the dose sometimes causes a large change in the level of free phenytoin in the blood.
What drug schedule is Dilantin?
Dilantin is used in the treatment of epilepsy; seizures; status epilepticus; neurosurgery; seizure prophylaxis during or following neurosurgery and belongs to the drug classes group I antiarrhythmics, hydantoin anticonvulsants.
What drugs do not show up on a DOT drug test?
DOT also does not prohibit employers from using tests of non-urine specimens under a non-DOT program….What CDL Drivers Need to Know
- Marijuana.
- Cocaine.
- Opiates – opium and codeine derivatives.
- Amphetamines and methamphetamines.
- Phencyclidine – PCP.