Which drug may cause toxicity when taken with grapefruit juice?

Which drug may cause toxicity when taken with grapefruit juice?

Here are examples of some types of drugs that grapefruit juice can cause problems (interact) with:

• Some statin drugs to lower cholesterol, such as Zocor (simvastatin) and Lipitor (atorvastatin).
• Some drugs that treat high blood pressure, such as Procardia and Adalat CC (both nifedipine).

Can I drink grapefruit juice with blood pressure medicine?

Calcium channel blockers They’re used as part of the treatment of conditions such as high blood pressure (hypertension) and coronary heart disease. Grapefruit juice interacts with some calcium channel blockers and increases the level of the medicine in your blood.

What’s wrong with grapefruit juice?

Grapefruit juice inhibits a chemical in the intestine needed to break down many drugs in the body. The absence of this chemical can lead to higher blood levels. In effect, the drug becomes more potent. This effect has been observed in nearly all calcium channel blockers, a group of drugs used to control blood pressure.

How much grapefruit juice causes a drug interaction?

One whole grapefruit or 200 mL of grapefruit juice is sufficient to cause clinically relevant increased systemic drug concentration and subsequent adverse effects.

Does drinking grapefruit juice lower blood pressure?

1. Citrus fruits. Citrus fruits, including grapefruit, oranges, and lemons, may have powerful blood-pressure-lowering effects. They’re loaded with vitamins, minerals, and plant compounds that may help keep your heart healthy by reducing heart disease risk factors like high blood pressure ( 4 ).

Does grapefruit juice make medicine stronger?

Compounds in grapefruit called furanocoumarin chemicals are the cause of the increased medication potency. These chemicals interact with the cytochrome P450 3A4 (CYP3A4) enzyme, found in the small intestine and liver, which partially inactivates many medications under normal circumstances.

How long does grapefruit juice stay in your system?

The interaction potential of even high amounts of grapefruit juice with CYP3A4 substrates dissipates within 3 to 7 days after ingestion of the last dose of grapefruit juice.

Can I take my supplements with grapefruit juice?

Dear S.M.: There is no evidence that vitamin or mineral supplements are affected by grapefruit juice in the same way it affects certain medications.

Does grapefruit actually burn fat?

Sorry, but grapefruit doesn’t burn fat. There have been a few studies about grapefruit and weight loss. In one, obese people who ate half a grapefruit before meals for 12 weeks lost more weight than those who didn’t eat or drink any grapefruit products.

Will grapefruit make you poop?

Citrus fruits like oranges, grapefruits, and mandarins are high in fiber and contain several compounds that can reduce constipation, including pectin and naringenin.

How fast does grapefruit burn fat?

Popularized as the “Hollywood diet,” the grapefruit diet involves eating grapefruit or drinking its juice with every meal. Supporters of the diet claim grapefruit can help burn fat, quickly leading to weight loss in as few as 12 days.

Does pineapple burn belly fat?

Pineapple and Papaya: These two tropical fruits contain the enzyme bromelain, which has anti-inflammatory properties and shrinks belly fat.

Does apple cider vinegar burn belly fat?

According to this study, adding 1 or 2 tablespoons of apple cider vinegar to your diet can help you lose weight. It can also reduce your body fat percentage, make you lose belly fat and decrease your blood triglycerides. This is one of a few human studies that have investigated vinegar’s effects on weight loss.

What are the 5 foods that cause belly fat?

Here are 12 things that make you gain belly fat.

• Sugary Foods and Beverages. Many people take in more sugar every day than they realize.
• Alcohol. Alcohol can have both healthful and harmful effects.
• Trans Fats.
• Inactivity.
• Low-Protein Diets.
• Menopause.
• The Wrong Gut Bacteria.
• Fruit Juice.